Utility and limitations of T. gondii-specific IgM serum antibodies in the diagnosis of congenital toxoplasmosis in Porto Alegre.

نویسنده

  • Rima McLeod
چکیده

A toxoplasmose congênita está associada a considerável morbidade quando não tratada. A partir do momento da descoberta de anticorpos IgM específicos contra Toxoplasma gondii em lactentes, a determinação do diagnóstico da infecção inclui a detecção de anticorpos IgM específicos contra este protozoário no soro do recém-nascido. No entanto, ainda não foi definido se esse teste apresenta diferenças e quão robusto ele é em diferentes populações e localidades. Os doutores Lago, Oliveira e Bender descreveram sua experiência com a presença de IgM contra T. gondii em soros obtidos de lactentes infectados congenitamente e cujas mães foram testadas no pré-natal, ou mães e bebês foram testados ou somente bebês foram testados, no período neonatal em um programa de triagem. Eles também observaram por quanto tempo ainda é possível detectar a imunoglobulina M anti-T. gondii no soro de crianças com toxoplasmose congênita, em um estudo cuidadosamente realizado e bem descrito.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Utility and limitations of T. gondii-specific IgM serum antibodies in the diagnosis of congenital toxoplasmosis

Congenital toxoplasmosis is associated with considerable morbidity when untreated. From the time of the discovery of T. gondii-specific IgM in infants, establishing the diagnosis of this infection has included the detection of T. gondii-specific IgM antibodies in serum of the newborn infant. However, whether this differs and the robustness of this test in different populations and regions has n...

متن کامل

Seroprevalence of Toxoplasma gondii Infection among Pregnant Women Admitted at Shahid Akbar Abadi Hospital, Tehran, Iran, 2010-2013

Introduction : Toxoplasmosis, caused by Toxoplasma gondii, is a protozoan parasitic infection distributed worldwide. Early infection by this protozoa can lead to abortion and congenital toxoplasmosis in pregnant women. This study was conducted to determine the seroprevalence of T. gondii infection among pregnant women referring to Shahid Akbar Abadi Hospital, Tehran, Iran during 2010-2013. Meth...

متن کامل

Diagnosis of congenital toxoplasmosis by two-dimensional immunoblot differentiation of mother and child immunoglobulin g profiles.

Differentiation between the specific immunoglobulin G (IgG) response to Toxoplasma gondii by a mother and her newborn child is helpful in the diagnosis of congenital infection with T. gondii in newborns without T. gondii-specific IgM and/or IgA antibodies at birth. Previous methods include immunoblotting and complexing T. gondii antigen with the sera from the mother and child and comparing the ...

متن کامل

Toxoplasmosis Seroepidemiology in Serum of Suspected Patients Referring to Medical Lab, 2013

Introduction: Toxoplasmosis is Zoonoses among humans and animals with cosmopolitan distribution. Acquired form of the disease often has no symptoms or discomfort of swollen lymph nodes and associated Chorioretinitis. The congenital form of the disease from mother to fetus via the placenta is delivered. Congenital infection may cause abortion or damage the central nervous system and eye disorde...

متن کامل

A Serological and Molecular study on Toxoplasma gondii infection in sheep and goat in Tabriz

Toxoplasmosis is an important zoonotic diseases in human and animals. The disease caused by the protozoan Toxoplasma gondii. To determine the infection rate of toxoplasmosis in sheep and goats in east Azarbaijan province of Iran a total of 186 sera, 13 fetal brains, 13 cotyledons and 34 whole blood samples were collected from sheep and goats in Tabriz abattoir during the year 2010. Serum sample...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Jornal de pediatria

دوره 90 4  شماره 

صفحات  -

تاریخ انتشار 2014